Imishini ingasetshenziswa embonini yezemithi, yokudla, yamakhemikhali nakwezinye izimboni ukuze kugxilwe futhi kugcwaliswe inqwaba yezinto eziwuketshezi kanye nokubuyiswa kwezinyibilikisi eziphilayo, kanye nokubuyiswa kokuhwamuka kwamanzi angcolile okukhiqiza. Isebenza kakhulu ekukhiqizeni umshayeli noma ucwaningo lwelabhorethri Lokuhlola lwamabhizinisi anamandla amancane okukhiqiza. Okokusebenza kungasetshenziswa ngaphansi kwengcindezi engemihle noma ingcindezi yomoya, futhi ingasetshenziselwa ukukhiqiza okuqhubekayo noma kwezikhawu. Ingasetshenziswa ezintweni ezihlukahlukene futhi inokuguquguquka okunamandla.Ithangi lokuhlushwa eliyindilinga lakhiwe ngokuyinhloko ngomzimba oyinhloko, i-condenser, isihlukanisi esiwuketshezi oluwuketshezi kanye nomphongolo wokwamukela uketshezi. Ingasetshenziselwa ukugxilisa ingqondo kanye nokukhishwa kwe-distillation ye-feed liquid kanye nokubuyiselwa kwe-solvent ephilayo ezimbonini zemithi, zokudla kanye namakhemikhali. Ngenxa yokusetshenziswa kwe-vacuum concentration, isikhathi sokuhlushwa sifushane futhi izingxenye ezisebenzayo zezinto ezizwela ukushisa ngeke zonakaliswe. Imishini nezingxenye zokuxhumana zenziwa ngensimbi engagqwali, enokumelana nokugqwala okuhle nokuqina.